Efficacy and Safety of Dual-target CAR-T Therapy for Newly Diagnosed High-Risk Multiple Myeloma

Efficacy and Safety of Dual-target CAR-T Therapy for Newly Diagnosed High-Risk Multiple Myeloma

2024.09.14
The 29th Annual Meeting of the European Hematology Association (EHA) was grandly held in Madrid, Spain, from June 13 to 16, 2024. At this EHA conference, a study (S200) by Professors Juan Du and Jing Lu from Shanghai Changzheng Hospital was selected for an oral presentation. This study explored the efficacy and safety of GC012F in the first-line treatment of newly diagnosed high-risk multiple myeloma patients eligible for transplantation. To discuss the study and the treatment of multiple myeloma, "Oncology Frontier - Hematology Frontier" conducted an interview with Professor Jing Lu.
Dr. Baohui Han Analyzes the Relationship Between PD-L1 Expression and Crizotinib Efficacy in ROS-1 Fusion-Positive NSCLC

Dr. Baohui Han Analyzes the Relationship Between PD-L1 Expression and Crizotinib Efficacy in ROS-1 Fusion-Positive NSCLC

2024.09.12
The development of modern oncology has provided a variety of groundbreaking treatment options for lung cancer, making it one of the most rapidly evolving solid tumors. To help clinical physicians gain an in-depth and comprehensive understanding of the significant advancements in this field, "Oncology Frontier" has joined forces with Dr. Hua Zhong and Dr. Baohui Han, Director of the Department of Respiratory and Critical Care Medicine at Shanghai Jiao Tong University School of Medicine Affiliated Chest Hospital,  to create a clinical progress series called "Zhong's Insights, Hui's Wisdom." By interpreting high-quality clinical studies in the field of lung cancer, this series aims to promote the improvement of clinical diagnostic and treatment practices. In this 23rd issue of the “Zhong's Insights, Hui's Wisdom” series, Dr. Hua Zhong and Dr. Baohui Han provide their expert analysis on the relationship between PD-L1 expression levels and the efficacy of first-line crizotinib treatment in ROS-1 fusion-positive non-small cell lung cancer (NSCLC) patients. The study was published in Lung Cancer by the Department of Respiratory and Critical Care Medicine at Shanghai Jiao Tong University School of Medicine Affiliated Chest Hospital, with Dr. Runbo Zhong as the corresponding author.
EHA 2024 | Conference Chairman Professor Antonio Almeida: Join Hands to Create the Future of Hematology Together

EHA 2024 | Conference Chairman Professor Antonio Almeida: Join Hands to Create the Future of Hematology Together

2024.07.08
The 29th Annual Congress of the European Hematology Association (EHA) was held in Madrid, Spain, from June 13 to 16, 2024. This conference is the largest international event in the field of European hematology, attracting numerous internationally renowned experts and scholars every year to share and discuss innovative ideas, the latest scientific research, and clinical research results in the field of hematology. At this conference, "Oncology Frontier - Hematology Frontier" specially invited Professor Antonio Almeida, the Chairman of the EHA Conference and the founding dean of the Hospital da Luz and Católica Medical School in Lisbon, Portugal, Lisbon, Portugal, to discuss the main highlights and important progress of the conference, covering a range of topics including breakthrough research, international cooperation, and the future challenges in the field of hematology.
ESMO BC 2024 | Professor Yiding Chen: Updated CAPItello-291 Study Data Pioneers Precision Therapy for the PAM Pathway in the Post-CDK4/6i Era

ESMO BC 2024 | Professor Yiding Chen: Updated CAPItello-291 Study Data Pioneers Precision Therapy for the PAM Pathway in the Post-CDK4/6i Era

2024.06.09
On May 16, 2024, the European Society for Medical Oncology Breast Cancer Annual Meeting (ESMO BC) reported updated results from the CAPItello-291 study (183MO). The data showed that the AKT inhibitor capivasertib combined with fulvestrant provided benefits in second-line treatment without affecting the benefits of subsequent treatments. This further solidified capivasertib's role in the post-CDK4/6 inhibitor (CDK4/6i) era, leading the way in precision therapy for HR+ breast cancer. Oncology Frontier interviewed Professor Yiding Chen from The Second Affiliated Hospital of Zhejiang University School of Medicine to analyze the progress of the CAPItello-291 study and discuss superior treatment options in the post-CDK4/6i era from mechanisms to clinical applications.
ESMO 2023丨Andrea Nccchi: Novel Intravesical Drug Delivery System Helps Bladder Cancer Patients Preserve Bladder, Reduce Risk of Recurrence

ESMO 2023丨Andrea Nccchi: Novel Intravesical Drug Delivery System Helps Bladder Cancer Patients Preserve Bladder, Reduce Risk of Recurrence

2024.02.18
At the 2023 European Society of Medical Oncology (ESMO 2023), Dr. Andrea Nccchi reported a phase 2b clinical study at the mini oral presentation, using a new intravesical local chemotherapy delivery system. TAR200 is expected to become a treatment method for patients with high-risk non-muscle invasive bladder (HR MIBC) to reduce disease recurrence. In addition, ESMO 2023 also reported TAR201 and EV-302 study. Dr. Andrea Nccchi shared his views on these latest studies in an interview with " Oncology Frontier ".