Engaging in a critical discussion on the topic of “When can we cure patients with metastatic sarcoma?” Professor Silvia Stacchiotti provided invaluable insights during an exclusive interview with Oncology Frontier at the European Society for Medical Oncology (ESMO). In this dialogue, Professor Stacchiotti reflects on the key factors that, in her expert opinion, play pivotal roles in determining the success of curing metastatic sarcoma. Let’s delve into the nuances of this complex subject through the eyes of a distinguished oncologist.