Professors Bin Song & Yuan Peng: How Should We Choose CDK4/6 Inhibitors for Adjuvant Endocrine Therapy Intensification?

Professors Bin Song & Yuan Peng: How Should We Choose CDK4/6 Inhibitors for Adjuvant Endocrine Therapy Intensification?

For patients with hormone receptor–positive (HR+) early breast cancer, when intensifying adjuvant endocrine therapy with a CDK4/6 inhibitor, should abemaciclib or ribociclib be preferred? At the 2025 Summer Breast Cancer Forum · Northern Salon, Professors Bin Song of Shanxi Bethune Hospital and Yuan Peng of Peking University People’s Hospital debated this question during the “Debate” session. Here, in Oncology Frontier’s “In-Depth” column, they share their perspectives supported by evidence.
Professor Cuizhi Geng: Advancing Standardized Care and Technological Innovation to Drive Homogeneity in Regional Breast Cancer Treatment

Professor Cuizhi Geng: Advancing Standardized Care and Technological Innovation to Drive Homogeneity in Regional Breast Cancer Treatment

The 16th Yan Zhao Breast Cancer Forum was held in Shijiazhuang from August 27–31, 2025. The event was jointly organized by the Breast Cancer Committee of the Hebei Anti-Cancer Association and multiple specialty committees, co-organized by the Beijing Breast Disease Prevention and Treatment Society, and hosted by the Fourth Hospital of Hebei Medical University and the Hebei Breast Disease Diagnosis and Treatment Center. This year’s forum emphasized standardization and innovation in breast cancer diagnosis and treatment, with highlights including guideline roadshows and robotic surgery. During the meeting, Oncology Frontier interviewed the conference chair, Professor Cuizhi Geng of the Fourth Hospital of Hebei Medical University, who shared insights on the forum highlights, the role of guideline dissemination, strategies for regional treatment homogeneity, and the clinical application and challenges of robot-assisted breast surgery.
Professor John Mascarenhas Details Breakthrough Safety and Efficacy Data of INCA33989 in Patients with ET丨EHA 2025

Professor John Mascarenhas Details Breakthrough Safety and Efficacy Data of INCA33989 in Patients with ET丨EHA 2025

The 2025 European Hematology Association (EHA) Annual Meeting was recently held, bringing together top global experts in the field of hematologic malignancies to discuss the latest research findings and future directions. In the highly anticipated "Late-Breaking Abstract" session, Professor John Mascarenhas from the Icahn School of Medicine at Mount Sinai presented clinical study data on INCA33989, a novel, first-in-class monoclonal antibody specific to mutant calreticulin (CALR). The study results showed that INCA33989 demonstrated excellent safety and revolutionary therapeutic potential in previously treated patients with Essential Thrombocythemia (ET), with the potential to change the current treatment landscape