EBMT 2026 China Voice | Professor Xing-Yu Cao: Sequential CD7 CAR-T Followed by Second Transplant Improves Survival to Nearly 50% in Post-Transplant Relapsed T-ALL/LBL

EBMT 2026 China Voice | Professor Xing-Yu Cao: Sequential CD7 CAR-T Followed by Second Transplant Improves Survival to Nearly 50% in Post-Transplant Relapsed T-ALL/LBL

Patients with T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LBL) who relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) have an extremely poor prognosis. Historically, treatment options have been limited, and even with a second transplant, long-term survival has remained below 30%. There is therefore an urgent need for more effective therapeutic strategies.
EAU26 | Professor Yi-Jun Shen on the HERO Study: Disitamab Vedotin Plus BCG Shows Promise in HR-NMIBC 

EAU26 | Professor Yi-Jun Shen on the HERO Study: Disitamab Vedotin Plus BCG Shows Promise in HR-NMIBC 

Non–muscle-invasive bladder cancer (NMIBC) carries a substantial risk of postoperative recurrence, particularly in high-risk and very high-risk patients, where the 5-year recurrence rate can exceed 50%. In recent years, beyond traditional Bacillus Calmette–Guérin (BCG) intravesical therapy, the emergence of immune checkpoint inhibitors (ICIs) and antibody–drug conjugates (ADCs) has provided new therapeutic options to reduce recurrence risk in high-risk NMIBC.
Voices from China at the EBMT Annual Meeting Prof. Hui Wang / Prof. Man Chen: CD72 as a Meaningful Marker and Target for MRD Assessment After CD19 CAR-T Therapy in B-ALL

Voices from China at the EBMT Annual Meeting Prof. Hui Wang / Prof. Man Chen: CD72 as a Meaningful Marker and Target for MRD Assessment After CD19 CAR-T Therapy in B-ALL

Although CD19 CAR-T therapy achieves high remission rates in relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL), relapse driven by CD19 antigen loss poses a major challenge for MRD monitoring and long-term disease management. Identifying more stable biomarkers has therefore become essential for improving response assessment and prognostic evaluation.
EAU26 Afternoon Dialogue | Prof. Kan Gong: Large-Scale Chinese VHL Cohort Reveals Distinct Mutation Patterns and Clinical Implications 

EAU26 Afternoon Dialogue | Prof. Kan Gong: Large-Scale Chinese VHL Cohort Reveals Distinct Mutation Patterns and Clinical Implications 

The 2026 European Association of Urology Annual Congress (EAU26), held in London, once again served as a premier platform showcasing cutting-edge advances in urologic oncology. At this year’s meeting, Prof. Kan Gong and his team from Peking University First Hospital presented a series of impactful studies focusing on von Hippel–Lindau (VHL) syndrome–associated renal cell carcinoma in the Chinese population.
Prof. Enrique Gallardo: Final OS Results from PEACE-3 Trial — Enzalutamide Plus Radium-223 Reshapes the mCRPC Treatment Landscape

Prof. Enrique Gallardo: Final OS Results from PEACE-3 Trial — Enzalutamide Plus Radium-223 Reshapes the mCRPC Treatment Landscape

The 2026 American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO GU 2026) has successfully concluded, bringing forward several landmark advances in prostate cancer. Among them, the final overall survival (OS) results from the EORTC 1333/PEACE-3 trial represent a major milestone in the management of metastatic castration-resistant prostate cancer (mCRPC) with bone metastases.
Shifting Paradigms in MIBC Diagnosis: How Multimodal Imaging Staging Optimizes Clinical Decision-Making 

Shifting Paradigms in MIBC Diagnosis: How Multimodal Imaging Staging Optimizes Clinical Decision-Making 

During the recent academic session, Professor Antoine Van Der Heijden from Radboud University Medical Center (Nijmegen, NL) shared comprehensive insights into the management of Muscle-Invasive Bladder Cancer (MIBC). The presentation focused on the clinical significance of histological subtypes, the inherent limitations of traditional Transurethral Resection of Bladder Tumor (TURBT), and the emerging value of MRI and Vi-RADS scoring in precision staging.
36% Reduction in DFS Risk: POTOMAC Study Validates Immuno-Combination Therapy for Elderly Patients with High-Risk NMIBC 

36% Reduction in DFS Risk: POTOMAC Study Validates Immuno-Combination Therapy for Elderly Patients with High-Risk NMIBC 

At a recent academic symposium, Professor Joan Palou from the Department of Urology, Universitat Autònoma de Barcelona, Spain, presented the latest subgroup analysis from the POTOMAC study. The presentation focused on the efficacy and safety of one year of durvalumab (D) in combination with Bacillus Calmette-Guérin (BCG) induction and maintenance therapy for BCG-naïve, high-risk non-muscle-invasive bladder cancer (NMIBC) patients aged ≥65 years.
ASCO GU On-Site Report | Prof. Xinan Sheng: A China-Developed Targeted–Immunotherapy Combination Opens a New Era of Bladder-Preserving Treatment for MIBC

ASCO GU On-Site Report | Prof. Xinan Sheng: A China-Developed Targeted–Immunotherapy Combination Opens a New Era of Bladder-Preserving Treatment for MIBC

The treatment landscape for muscle-invasive bladder cancer (MIBC) is undergoing profound transformation. Although cisplatin-based neoadjuvant chemotherapy remains the traditional standard of care, the pathological complete response (pCR) rate has long remained at approximately 30%–40%, and a substantial proportion of patients cannot receive cisplatin due to factors such as renal insufficiency. Consequently, more effective preoperative treatment strategies are urgently needed.
Annual Review | Precision Stratification and Synergistic Combinations: Prof. Xinan Sheng Reviews Key Advances in Renal Cell Carcinoma in 2025

Annual Review | Precision Stratification and Synergistic Combinations: Prof. Xinan Sheng Reviews Key Advances in Renal Cell Carcinoma in 2025

In 2025, the field of renal cell carcinoma (RCC) advanced decisively along the dual pathways of precision and combination therapy. Landmark developments reshaped clinical practice across disease stages: perioperative targeted–immunotherapy combinations that altered surgical paradigms for locally advanced disease; long-term survival data confirming the durability of first-line immunotherapy-based regimens; innovative later-line strategies overcoming therapeutic resistance; and biomarker-driven approaches enabling molecularly guided treatment for rare non–clear cell subtypes.